Evaluation of the clotting defect in a factor XII-deficient kindred.

Abstract

A family with factor XII severe congenital deficiency is described. Factor XII activity and factor XII antigen were both undetectable in the propositus plasma; levels of FXII:C and FXII:Ag were intermediate in heterozygotes. Plasma prekallikrein activity was low in the propositus, whereas normal levels of antigen could be found, suggesting a defect of… (More)

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@article{Chistolini1985EvaluationOT, title={Evaluation of the clotting defect in a factor XII-deficient kindred.}, author={Antonio Chistolini and Maria Gabriella Mazzucconi and M. Motta and Sandro Paolo Solinas and M. C. Tirindelli and G. Mariani}, journal={La Ricerca in clinica e in laboratorio}, year={1985}, volume={15 3}, pages={241-5} }