Evaluation of the cardiac actin gene in Doberman Pinschers with dilated cardiomyopathy.

@article{Meurs2001EvaluationOT,
  title={Evaluation of the cardiac actin gene in Doberman Pinschers with dilated cardiomyopathy.},
  author={Kathryn M. Meurs and A L Magnon and Alan W. Spier and Matthew W. Miller and Linda B. Lehmkuhl and Jeffry A Towbin},
  journal={American journal of veterinary research},
  year={2001},
  volume={62 1},
  pages={33-6}
}
OBJECTIVE To evaluate the coding region of the cardiac actin gene in Doberman Pinschers with dilated cardiomyopathy (DCM) for mutations that could be responsible for the development of the condition ANIMALS 28 dogs (16 Doberman Pinschers with DCM and 12 mixed-breed control dogs). PROCEDURE Ten milliliters of blood was collected from each dog for DNA extraction. Polymerase chain reaction (PCR) primers were designed to amplify canine exonic regions, using the sequences of exons 2 to 6 of the… CONTINUE READING
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