Evaluation of the anxiolytic properties of myristicin, a component of nutmeg, in the male Sprague-Dawley rat.

@article{Leiter2011EvaluationOT,
  title={Evaluation of the anxiolytic properties of myristicin, a component of nutmeg, in the male Sprague-Dawley rat.},
  author={Emily Leiter and Gavin Hitchcock and Stuart Godwin and Michelle Johnson and William Sedgwick and Wendy S Jones and Suzanne McCall and Thomas E Ceremuga},
  journal={AANA journal},
  year={2011},
  volume={79 2},
  pages={109-14}
}
The purpose of this study was to investigate the anxiolytic effects of myristicin, a major compound found in nutmeg, and its potential interaction with the gamma-aminobutyric acid (GABA(A)) receptor in male Sprague-Dawley rats. Nutmeg has traditionally been used as a spice in food preparation and as an herbal remedy in the treatment of many medical conditions, including anxiety. Fifty-five rats were divided equally into 5 groups: control (vehicle); myristicin; midazolam (positive control… CONTINUE READING

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