Evaluation of the antineoplastic activity of guduchi (Tinospora cordifolia) in cultured HeLa cells.

@article{Jagetia1998EvaluationOT,
  title={Evaluation of the antineoplastic activity of guduchi (Tinospora cordifolia) in cultured HeLa cells.},
  author={Ganesh Chandra Jagetia and Vijayashree Nayak and Mamidipudi Srinivasa Vidyasagar},
  journal={Cancer letters},
  year={1998},
  volume={127 1-2},
  pages={
          71-82
        }
}
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116 Citations
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41
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116 Citations

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Effect of Coccinia indica on Blood Glucose, Insulin and Key Hepatic Enzymes in Experimental Diabetes
TLDR
It is demonstrated that all the guduchi extracts were able to enhance the effect of radiation significantly and the most effective extract was Mch, where the reduction in the surviving fraction of cells was higher than either Aqu, Met, Met + irradiation or Dox - irradiation group.
Determination of Antineoplastic Activity of Rohituka, Aphanamixis Polystachya (Wall) RN Parker in Hela Cells: Correlation with Clonogenicity and DNA Damage
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This study demonstrates that APE is able to kill HeLa cells effectively and this cell killing effect of APE may be due its ability to induce DNA damage.
Evaluation of the antineoplastic activity of guduchi (Tinospora cordifolia) in Ehrlich ascites carcinoma bearing mice.
TLDR
Evaluated the effectiveness of TCE in the various stages of tumor development, where 50 mg/kg TCE was administered intraperitoneally after 1, 3, 6, 9, 12 or 15 d of tumor inoculation and these days have been arbitrarily designated as stage I, II, III, IV or V, respectively for reasons of clarity.
Evaluation of anticancer activity of the alkaloid fraction of Alstonia scholaris (Sapthaparna) in vitro and in vivo
TLDR
The anticancer effect of various doses of an alkaloid fraction of Sapthaparna, Alstonia scholaris (ASERS), was studied in vitro in cultured human neoplastic cell lines and in Ehrlich ascites carcinoma bearing mice.
Alteration in the Radiosensitivity of HeLa Cells by Dichloromethane Extract of Guduchi (Tinospora cordifolia)
TLDR
HeLa cells treated with TCE showed an increase in lactate dehydrogenase and decrease in glutathioneS-transferase activity at all postirradiation times, and Lipid peroxidation increased up to 4 hours postir Radiation and declined gradually up to 12 hours postIRradiation.
Dichloromethane Extract of Giloe (Tinospora Cordifolia, Wild) Increases the Radiosensitivity of Cultured Hela Cells Exposed to Different Doses of Γ-Radiation
TLDR
An attempt has been made to evaluate the potential of dichloromethane extract of giloe i.e. Tinospora cordifolia (TCE) in cultured HeLa cells and found that the TCE treatment increased the radiosensitivity of He La cells by reducing glutathione-S-transferase activity and increasing the activity of lactate dehydrogenase and lipid peroxidation.
Antiproliferative activity of Tinospora cordifolia determined by cell count and trypan blue dye exclusion method in mcf-7 cells
TLDR
The result suggest that aqueous and hydro-alcoholic extracts of Tinospora cordifolia could reduce cell count and cell viability in MCF-7 cell line and act as effective anti-proliferative agent in mammary tumor.
Cytotoxic and apoptotic activities of extracts of Withania somnifera and Tinospora cordifolia in human breast cancer cells
TLDR
Potential anti-cancer activities of the ethanolic and extracts of TC and WS against human breast cancer cells are revealed and their potential for drug discovery is revealed.
In vitro antitubercular, anticancer activities and IL-10 expression in HCT-116 cells of Tinospora sinensis (Lour.) Merr. leaves extract
TLDR
Among all extracts, n-hexane leaf extract was found to be potent against inhibition of colon cancer cells (HCT-116) and Mycobacteria, with significant immunostimulant activity.
Effect of acyclovir on the radiation-induced micronuclei and cell death.
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