Evaluation of the anti-osteoporotic effects of metformin and sitagliptin in postmenopausal diabetic women

  title={Evaluation of the anti-osteoporotic effects of metformin and sitagliptin in postmenopausal diabetic women},
  author={Sahar Kamal Hegazy},
  journal={Journal of Bone and Mineral Metabolism},
Osteoporosis is the most important metabolic bone disease in patients with diabetes mellitus. Several studies have documented that metformin is osteogenic in vitro. In contrast, others showed no effect of metformin on the osteogenic differentiation of bone marrow-derived mesenchymal stem cells. Incretin hormones have received much attention because of their beneficial effects beyond glycemia, including on bone health. The study evaluated the anti-osteoporotic effect of metformin and sitagliptin… CONTINUE READING


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