Evaluation of the anti-inflammatory effects of phloretin and phlorizin in lipopolysaccharide-stimulated mouse macrophages.

@article{Chang2012EvaluationOT,
  title={Evaluation of the anti-inflammatory effects of phloretin and phlorizin in lipopolysaccharide-stimulated mouse macrophages.},
  author={W. F. Chang and Wen-Chung Huang and Chian-Jiun Liou},
  journal={Food chemistry},
  year={2012},
  volume={134 2},
  pages={972-9}
}
Many reports suggest that phloretin and phlorizin have antioxidant properties and can inhibit glucose transportation, the anti-inflammatory effects and mechanism of phloretin and phlorizin remain unclear. This study aims to evaluate the anti-inflammatory effects of phloretin and phlorizin in LPS-stimulated murine RAW264.7 macrophages. RAW264.7 cells were pretreated with various concentrations of phloretin or phlorizin (3-100 μM) and cell inflammatory responses were induced with LPS. Pretreated… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 30 references

Macrophages, inflammation, and insulin resistance.

Annual review of physiology • 2010
View 6 Excerpts
Highly Influenced

Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases.

Microbiology and molecular biology reviews : MMBR • 2011
View 3 Excerpts
Highly Influenced

Phlorizin: a review.

Diabetes/metabolism research and reviews • 2005
View 6 Excerpts
Highly Influenced

The antioxidant activity of phloretin: The disclosure of a new antioxidant pharmacophore in flavonoids

B. M. Rezk, G. R. Haenen, W. J. van der Vijgh, A. Bast
Molecular Cell Biology Research Communications, • 2002
View 3 Excerpts
Highly Influenced

Advanced dental disease in people with severe mental illness: systematic review and meta-analysis.

The British journal of psychiatry : the journal of mental science • 2011
View 1 Excerpt

Pro-inflammatory mechanisms in sepsis.

Contributions to microbiology • 2011
View 2 Excerpts

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