Evaluation of the anti-inflammatory, anti-nociceptive and gastric effects of Ginkgo biloba in the rat.

  title={Evaluation of the anti-inflammatory, anti-nociceptive and gastric effects of Ginkgo biloba in the rat.},
  author={O. Abdel-Salam and A. R. Baiuomy and S. El-batran and M. Arbid},
  journal={Pharmacological research},
  volume={49 2},
  • O. Abdel-Salam, A. R. Baiuomy, +1 author M. Arbid
  • Published 2004
  • Medicine
  • Pharmacological research
  • Ginkgo biloba extract (GbE) was assessed in models of acute inflammation induced by carrageenan, formalin or capsaicin in the rat, in models of nociceptive pain, such as hot-plate (55 degrees C) latency, tail-electric stimulation assay and capsaicin-induced paw licking and in the model of acute gastric damage induced by indomethacin. The agent showed marked anti-inflammatory activity in the carrageenan model of paw oedema. When given subcutaneously (s.c.) (25 and 50 mg kg(-1)) 30 min before… CONTINUE READING
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