Evaluation of the acute toxicity, phytochemical constituents and anti - ulcer properties of methanolic leaf extract of Annona muricata in mice

@article{Omoja2014EvaluationOT,
  title={Evaluation of the acute toxicity, phytochemical constituents and anti - ulcer properties of methanolic leaf extract of Annona muricata in mice},
  author={Valentine Uneojo Omoja and Thelma Ebele Ihedioha and G. Ifeanyi Eke and Iheanyi Kemdirim Peter-Ajuzıe and Samuel Ekere Okezie},
  journal={Journal of Intercultural Ethnopharmacology},
  year={2014},
  volume={3},
  pages={37-43}
}
This study investigated the acute toxicity, phytochemical constituents and anti - ulcer properties of methanolic leaf extract of Annona muricata in mice. The anti - ulcer activity was evaluated using absolute ethanol-induced ulcer and aspirin-induced ulcer models in mice. An LD50 of 354.8 ± 8 mg/kg body weight, bw of the extract was obtained on oral administration. Investigation of the phytochemical constituents of the plant extract revealed the presence of saponins, alkaloids and traces of… Expand
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