Evaluation of the WHO criteria for antiretroviral treatment failure among adults in South Africa.

@article{Mee2008EvaluationOT,
  title={Evaluation of the WHO criteria for antiretroviral treatment failure among adults in South Africa.},
  author={Paul Mee and Katherine L. Fielding and Salome Charalambous and Gavin John Churchyard and Alison D Grant},
  journal={AIDS},
  year={2008},
  volume={22 15},
  pages={1971-7}
}
OBJECTIVE To assess the performance of WHO clinical and CD4 cell count criteria for antiretroviral treatment (ART) failure among HIV-infected adults in a workplace HIV care programme in South Africa. DESIGN Cohort study. METHODS We included initially ART-naive participants who remained on first-line therapy and had an evaluable HIV viral load result at the 12-month visit. WHO-defined clinical and CD4 cell count criteria for ART failure were compared against a gold standard of virological… CONTINUE READING