Evaluation of the Transwell System for Characterization of Dissolution Behavior of Inhalation Drugs: Effects of Membrane and Surfactant.

@article{Rohrschneider2015EvaluationOT,
  title={Evaluation of the Transwell System for Characterization of Dissolution Behavior of Inhalation Drugs: Effects of Membrane and Surfactant.},
  author={Marc Rohrschneider and Sharvari Bhagwat and R. Krampe and V. Michler and J. Breitkreutz and G. Hochhaus},
  journal={Molecular pharmaceutics},
  year={2015},
  volume={12 8},
  pages={
          2618-24
        }
}
  • Marc Rohrschneider, Sharvari Bhagwat, +3 authors G. Hochhaus
  • Published 2015
  • Chemistry, Medicine
  • Molecular pharmaceutics
  • Assessing the dissolution behavior of orally inhaled drug products (OIDs) has been proposed as an additional in vitro test for the characterization of innovator and generic drug development. A number of suggested dissolution methods (e.g., commercially available Transwell or Franz cell systems) have in common a membrane which provides the separation between the donor compartment, containing nondissolved drug particles, and an acceptor (sampling) compartment into which dissolved drug will… CONTINUE READING
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