• DOI:10.1021/acs.molpharmaceut.5b00221
Corpus ID: 206685008

Evaluation of the Transwell System for Characterization of Dissolution Behavior of Inhalation Drugs: Effects of Membrane and Surfactant.

@article{Rohrschneider2015EvaluationOT,
  title={Evaluation of the Transwell System for Characterization of Dissolution Behavior of Inhalation Drugs: Effects of Membrane and Surfactant.},
  author={Marc Rohrschneider and Sharvari Bhagwat and R. Krampe and V. Michler and J. Breitkreutz and G. Hochhaus},
  journal={Molecular pharmaceutics},
  year={2015},
  volume={12 8},
  pages={
          2618-24
        }
}

Marc Rohrschneider, Sharvari Bhagwat, +3 authors G. Hochhaus

Published 2015

Chemistry, Medicine

Molecular pharmaceutics

Assessing the dissolution behavior of orally inhaled drug products (OIDs) has been proposed as an additional in vitro test for the characterization of innovator and generic drug development. A number of suggested dissolution methods (e.g., commercially available Transwell or Franz cell systems) have in common a membrane which provides the separation between the donor compartment, containing nondissolved drug particles, and an acceptor (sampling) compartment into which dissolved drug will… CONTINUE READING

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