Evaluation of the Safety and Protection Efficacy of spiC and nmpC or rfaL Deletion Mutants of Salmonella Enteritidis as Live Vaccine Candidates for Poultry Non-Typhoidal Salmonellosis

@article{Li2019EvaluationOT,
  title={Evaluation of the Safety and Protection Efficacy of spiC and nmpC or rfaL Deletion Mutants of Salmonella Enteritidis as Live Vaccine Candidates for Poultry Non-Typhoidal Salmonellosis},
  author={Qiuchun Li and Y. Zhu and Jingwei Ren and Zhuang Qiao and C. Yin and Honghong Xian and Y. Yuan and Shizhong Geng and Xin'An Jiao},
  journal={Vaccines},
  year={2019},
  volume={7}
}
  • Qiuchun Li, Y. Zhu, +6 authors Xin'An Jiao
  • Published 2019
  • Biology, Medicine
  • Vaccines
    • Salmonella enterica serovar Enteritidis (S. Enteritidis) is a host-ranged pathogen that can infect both animals and humans. Poultry and poultry products are the main carriers of S. Enteritidis, which can be transmitted to humans through the food chain. To eradicate the prevalence of S. Enteritidis in poultry farms, it is necessary to develop novel vaccines against the pathogen. In this study, we constructed two vaccine candidates, CZ14-1∆spiC∆nmpC and CZ14-1∆spiC∆rfaL, and evaluated their… CONTINUE READING
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    Development of Salmonella Enteritidis vaccine candidate based on streptomycin independent suppressor and metabolic drift rifampicin resistance-attenuating markers

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