Evaluation of the Role of the opgGH Operon in Yersinia pseudotuberculosis and Its Deletion during the Emergence of Yersinia pestis

@article{Quintard2015EvaluationOT,
  title={Evaluation of the Role of the opgGH Operon in Yersinia pseudotuberculosis and Its Deletion during the Emergence of Yersinia pestis},
  author={K{\'e}vin Quintard and Am{\'e}lie Dewitte and A. Reboul and E. Madec and S{\'e}bastien Bontemps-Gallo and Jacqueline Dondeyne and M. Marceau and M. Simonet and J. Lacroix and F. Sebbane},
  journal={Infection and Immunity},
  year={2015},
  volume={83},
  pages={3638 - 3647}
}
ABSTRACT The opgGH operon encodes glucosyltransferases that synthesize osmoregulated periplasmic glucans (OPGs) from UDP-glucose, using acyl carrier protein (ACP) as a cofactor. OPGs are required for motility, biofilm formation, and virulence in various bacteria. OpgH also sequesters FtsZ in order to regulate cell size according to nutrient availability. Yersinia pestis (the agent of flea-borne plague) lost the opgGH operon during its emergence from the enteropathogen Yersinia… Expand
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