Evaluation of the Induction of Immune Memory following Infant Immunisation with Serogroup C Neisseria meningitidis Conjugate Vaccines – Exploratory Analyses within a Randomised Controlled Trial

Abstract

AIM We measured meningococcal serogroup C (MenC)-specific memory B-cell responses in infants by Enzyme-Linked Immunospot (ELISpot) following different MenC conjugate vaccine schedules to investigate the impact of priming on immune memory. METHODS Infants aged 2 months were randomised to receive 1 or 2 doses of MenC-CRM197 at 3 or 3 and 4 months, 1 dose of… (More)
DOI: 10.1371/journal.pone.0101672

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@inproceedings{Khatami2014EvaluationOT, title={Evaluation of the Induction of Immune Memory following Infant Immunisation with Serogroup C Neisseria meningitidis Conjugate Vaccines – Exploratory Analyses within a Randomised Controlled Trial}, author={Ameneh Khatami and Elizabeth A. Clutterbuck and Amber J. Thompson and Jennifer A. McKenna and David Pace and Jacqueline Birks and Matthew D Snape and Andrew J Pollard}, booktitle={PloS one}, year={2014} }