Evaluation of the IL2/IL21, IL2RA and IL2RB genetic variants influence on the endogenous non-anterior uveitis genetic predisposition

@inproceedings{Cenit2012EvaluationOT,
  title={Evaluation of the IL2/IL21, IL2RA and IL2RB genetic variants influence on the endogenous non-anterior uveitis genetic predisposition},
  author={Maria del Carmen Cenit and Ana Citlali M{\'a}rquez and Miguel Cordero-Coma and Alex Fonollosa and Alfredo M Adan and Agust{\'i}n Mart{\'i}nez-Berriotxoa and V{\'i}ctor Llorenç and David D{\'i}az Valle and Ricardo Blanco and Joaqu{\'i}n Ca{\~n}al and Manuel D{\'i}az-Ll{\'o}pis and Jos{\'e} Luis Garc{\'i}a Serrano and Enrique de Ram{\'o}n and Mar{\'i}a Jos{\'e} del R{\'i}o and Marina Bego{\~n}a Gorro{\~n}o- Echebarr{\'i}a and Jos{\'e} Manuel Mart{\'i}n-Villa and Norb{\'e}rto Ortego-Centeno and Javier Martin},
  booktitle={BMC Medical Genetics},
  year={2012}
}
Recently, different genetic variants located within the IL2/IL21 genetic region as well as within both IL2RA and IL2RB loci have been associated to multiple autoimmune disorders. We aimed to investigate for the first time the potential influence of the IL2/IL21, IL2RA and IL2RB most associated polymorphisms with autoimmunity on the endogenous non-anterior uveitis genetic predisposition. A total of 196 patients with endogenous non-anterior uveitis and 760 healthy controls, all of them from… CONTINUE READING

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