Evaluation of the HIV-1 reverse transcriptase inhibitory properties of extracts from some medicinal plants in Kenya.

@article{Rukunga2002EvaluationOT,
  title={Evaluation of the HIV-1 reverse transcriptase inhibitory properties of extracts from some medicinal plants in Kenya.},
  author={G. Rukunga and M. Kofi-Tsekpo and M. Kurokawa and S. Kageyama and G. Mungai and J. M. Muli and F. Tolo and R. Kibaya and C. Muthaura and J. N. Kanyara and P. Tukei and K. Shiraki},
  journal={African journal of health sciences},
  year={2002},
  volume={9 1-2},
  pages={
          81-90
        }
}
Extracts from twenty two medicinal plants popularly used in preparing traditional remedies in Kenya were screened for activity against the HIV-1 reverse transcriptase. The screening procedure involved the use of tritium labeled thymidine triphosphate as the enzyme substrate and polyadenylic acid.oligodeoxythymidylic acid [poly(rA).p(dT)12-18] as the template primer dimer. Foscarnet was used as a positive control in these experiments. At a concentration of 100 microg/ml, extracts from eight of… Expand
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