Evaluation of the Framingham risk score in the European Prospective Investigation of Cancer-Norfolk cohort: does adding glycated hemoglobin improve the prediction of coronary heart disease events?

@article{Simmons2008EvaluationOT,
  title={Evaluation of the Framingham risk score in the European Prospective Investigation of Cancer-Norfolk cohort: does adding glycated hemoglobin improve the prediction of coronary heart disease events?},
  author={Rebecca K. Simmons and Stephen J Sharp and S. Matthijs Boekholdt and Lincoln A Sargeant and Kay-tee Khaw and Nicholas J Wareham and Simon J Griffin},
  journal={Archives of internal medicine},
  year={2008},
  volume={168 11},
  pages={1209-16}
}
BACKGROUND There is a continuous relationship between glycated hemoglobin (HbA(1c)) and coronary heart disease (CHD) risk, even below diagnostic thresholds for diabetes mellitus. METHODS To evaluate the Framingham risk score in a UK population-based prospective cohort (European Prospective Investigation of Cancer [EPIC]-Norfolk) and to assess whether adding HbA(1c) improves the prediction of CHD. Participants aged 40 to 79 years were recruited from UK general practices, attended a health… CONTINUE READING

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