Evaluation of the Effects of Caffeic Acid Phenethyl Ester on Prostaglandin E2 and Two Key Cytokines Involved in Bleomycin-induced Pulmonary Fibrosis

@inproceedings{LarkiHarchegani2013EvaluationOT,
  title={Evaluation of the Effects of Caffeic Acid Phenethyl Ester on Prostaglandin E2 and Two Key Cytokines Involved in Bleomycin-induced Pulmonary Fibrosis},
  author={Amir Larki-Harchegani and Ali Asghar Hemmati and Ardeshir Arzi and Mehri Ghafurian-Boroojerdnia and Somayeh Shabib and Mohammad Reza Zadkarami and Saleh Esmaeilzadeh},
  booktitle={Iranian journal of basic medical sciences},
  year={2013}
}
OBJECTIVE(S) Pulmonary fibrosis (PF) is the most common outcome of a collection of diverse lung disorders known as interstitial lung diseases. It is proposed that alterations in the levels of fibrogenic mediators and the profibrotic/antifibrotic imbalance play a substantial role in the progression of PF in animal models and possibly in humans. Caffeic acid phenethyl ester (CAPE), an active component of propolis, has numerous biological effects. In the present study, the main objective was to… CONTINUE READING