Evaluation of the Effect of Ascorbic Acid Administration on Gene Expression Level of IL-6 and TNF-α Cytokines in Deceased Donors.

Abstract

Brain death is associated with increased inflammatory cytokines levels and poor graft quality to transplant. We aimed to evaluate the impact of Ascorbic Acid (AA) on the inflammatory status of Brain-Dead Donors (BDDs). Forty BDDs were randomly divided into two groups. Donor treatment (n=20) consisted of 100 mg/kg AA infusion 6 hours before donor operation… (More)

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@article{Kazemi2015EvaluationOT, title={Evaluation of the Effect of Ascorbic Acid Administration on Gene Expression Level of IL-6 and TNF-α Cytokines in Deceased Donors.}, author={Masoumeh Bahre Kazemi and Seyed Mohammad M. Tabei and Katayoun Najafizadeh and Jafar Mehrabi Sisakht and Soheila Milani and Mohammad Bagher Khosravi}, journal={Iranian journal of allergy, asthma, and immunology}, year={2015}, volume={14 2}, pages={149-57} }