Evaluation of the Antipsychotic Potential of Panax quinquefolium in Ketamine Induced Experimental Psychosis Model in Mice

@article{Chatterjee2011EvaluationOT,
  title={Evaluation of the Antipsychotic Potential of Panax quinquefolium in Ketamine Induced Experimental Psychosis Model in Mice},
  author={Manavi Chatterjee and Seema Singh and Reena Kumari and Anil Kumar Verma and Gautam Palit},
  journal={Neurochemical Research},
  year={2011},
  volume={37},
  pages={759-770}
}
The search for novel pharmacotherapy from medicinal plants for psychiatric illnesses has progressed significantly from the past few decades and their therapeutic potential has been assessed in a variety of animal models. The aim of our study was to screen one such plant, Panax quinquefolium (PQ), with significant neuroactive properties for its antipsychotic potential. A graded dose study with PQ at 12.5–200 mg/kg, p. o. showed differential effects against the ketamine induced hyperactivity in… CONTINUE READING
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