Evaluation of the Abbott realtime HCV genotype II RUO (GT II) assay with reference to 5'UTR, core and NS5B sequencing.

@article{Mallory2014EvaluationOT,
  title={Evaluation of the Abbott realtime HCV genotype II RUO (GT II) assay with reference to 5'UTR, core and NS5B sequencing.},
  author={Melanie A Mallory and Danijela X Lucic and Mitchell T Sears and Gavin A. Cloherty and David R. Hillyard},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2014},
  volume={60 1},
  pages={22-6}
}
BACKGROUND HCV genotyping is a critical tool for guiding initiation of therapy and selecting the most appropriate treatment regimen. OBJECTIVE To evaluate the concordance between the Abbott GT II assay and genotyping by sequencing subregions of the HCV 5'UTR, core and NS5B. STUDY DESIGN The Abbott assay was used to genotype 127 routine patient specimens and 35 patient specimens with unusual subtypes and mixed infection. Abbott results were compared to genotyping by 5'UTR, core and NS5B… CONTINUE READING
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