Evaluation of testicular biopsies for carcinoma in situ: immunohistochemistry is mandatory.

@article{Casteren2009EvaluationOT,
  title={Evaluation of testicular biopsies for carcinoma in situ: immunohistochemistry is mandatory.},
  author={Niels J van Casteren and Jos de Jong and Hans Stoop and Ewout Willem Steyerberg and Esther W. de Bekker-Grob and Gert R. Dohle and J. Wolter A. Oosterhuis and Leendert H J Looijenga},
  journal={International journal of andrology},
  year={2009},
  volume={32 6},
  pages={666-74}
}
Carcinoma in situ (CIS) is the common precursor of all type II testicular germ cell tumors (TGCTs), i.e. seminomas and non-seminomas, which can be diagnosed using a surgical biopsy. The objective of this study was to investigate the additional value of immunohistochemistry for the diagnosis of CIS in assessing testicular biopsies taken in the context of… CONTINUE READING