Evaluation of synthetic, M type-specific peptides as antigens in a multivalent group A streptococcal vaccine.

@article{Bruner2003EvaluationOS,
  title={Evaluation of synthetic, M type-specific peptides as antigens in a multivalent group A streptococcal vaccine.},
  author={Mark Bruner and Andrew G. James and Bernard Beall and George M. Carlone and Edwin P Ades and Scott Johnson and Jeannette Guarner and Jacquelyn S. Sampson},
  journal={Vaccine},
  year={2003},
  volume={21 21-22},
  pages={2698-703}
}
The recent development of emm gene sequence-based typing methodology has allowed group A streptococci (GAS) M serotype prevalence data to be determined. This information has been used to identify the components of a multivalent M protein peptide vaccine that could theoretically prevent most of the GAS-mediated diseases in the USA. In this study, we have… CONTINUE READING