Evaluation of spatially fractionated radiotherapy (GRID) and definitive chemoradiotherapy with curative intent for locally advanced squamous cell carcinoma of the head and neck: initial response rates and toxicity.

@article{Peagarcano2010EvaluationOS,
  title={Evaluation of spatially fractionated radiotherapy (GRID) and definitive chemoradiotherapy with curative intent for locally advanced squamous cell carcinoma of the head and neck: initial response rates and toxicity.},
  author={Jos{\'e} A Pe{\~n}agar{\'i}cano and Eduardo G. Moros and Vaneerat Ratanatharathorn and Yulong Yan and Peter Matthew Corry},
  journal={International journal of radiation oncology, biology, physics},
  year={2010},
  volume={76 5},
  pages={
          1369-75
        }
}
PURPOSE To present results and acute toxicity in 14 patients with bulky (>or=6 cm) tumors from locally advanced squamous cell carcinoma of the head and neck who received spatially fractionated radiotherapy (GRID) therapy to the bulky mass followed by concomitant chemoradiotherapy using simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT). METHODS AND MATERIALS GRID therapy to the GTV was delivered by creating one treatment field with a checkerboard pattern composed of… CONTINUE READING
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