Evaluation of sesquiterpene lactone fraction of Saussurea lappa on transudative, exudative and proliferative phases of inflammation

@article{Damre2003EvaluationOS,
  title={Evaluation of sesquiterpene lactone fraction of Saussurea lappa on transudative, exudative and proliferative phases of inflammation},
  author={A. Damre and A. S. Damre and M. Saraf},
  journal={Phytotherapy Research},
  year={2003},
  volume={17}
}
  • A. Damre, A. S. Damre, M. Saraf
  • Published 2003
  • Medicine, Biology
  • Phytotherapy Research
  • The sesquiterpene lactone fraction of Saussurea lappa roots was evaluated for its effect on the transudative, exudative and proliferative phases of inflammation using the cotton pellet granuloma assay in rats. The fraction (25–100 mg/kg, p.o.) showed significant dose‐dependent inhibition of the increase in wet weight of the cotton pellet at 3 h (transudative phase), leakage of dye from the bloodstream around granuloma at 24 h (exudative phase) and increase in dry weight of the cotton pellet on… CONTINUE READING
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