Evaluation of sesquiterpene lactone fraction of Saussurea lappa on transudative, exudative and proliferative phases of inﬂammation

A. Damre; A. S. Damre; M. Saraf

DOI:10.1002/PTR.1152

Corpus ID: 39651463

Evaluation of sesquiterpene lactone fraction of Saussurea lappa on transudative, exudative and proliferative phases of inﬂammation

@article{Damre2003EvaluationOS,
  title={Evaluation of sesquiterpene lactone fraction of Saussurea lappa on transudative, exudative and proliferative phases of inﬂammation},
  author={A. Damre and A. S. Damre and M. Saraf},
  journal={Phytotherapy Research},
  year={2003},
  volume={17}
}

A. Damre, A. S. Damre, M. Saraf

Published 2003

Medicine, Biology

Phytotherapy Research

The sesquiterpene lactone fraction of Saussurea lappa roots was evaluated for its effect on the transudative, exudative and proliferative phases of inﬂammation using the cotton pellet granuloma assay in rats. The fraction (25–100 mg/kg, p.o.) showed signiﬁcant dose‐dependent inhibition of the increase in wet weight of the cotton pellet at 3 h (transudative phase), leakage of dye from the bloodstream around granuloma at 24 h (exudative phase) and increase in dry weight of the cotton pellet on… CONTINUE READING

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