Evaluation of serum HER2 extracellular domain in early breast cancer patients: correlation with clinicopathological parameters and survival.

@article{Ludovini2008EvaluationOS,
  title={Evaluation of serum HER2 extracellular domain in early breast cancer patients: correlation with clinicopathological parameters and survival.},
  author={Vienna Ludovini and Stefania Gori and Mariantonietta Colozza and Lorenza Pistola and Eliana Rulli and Irene C Floriani and Eugenio Pacifico and Francesca Romana Tofanetti and Angelo Sidoni and Carlo Basurto and Antonio Rulli and Lucio Crin{\`o}},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2008},
  volume={19 5},
  pages={883-90}
}
BACKGROUND We explored the correlation between serum human epidermal growth factor receptor-2 (HER2) extracellular domain (ECD) and tissue HER2 status, their relationship with clinicopathological parameters and their impact on disease-free survival (DFS) and overall survival in early breast cancer patients. PATIENTS AND METHODS This prospective trial included patients with stage I-III breast cancer. Serum HER2 ECD levels were measured by two enzyme-linked immunosorbent assays before surgical… CONTINUE READING