Corpus ID: 19185986

Evaluation of sedative R51703 in cattle: effects on cardiorespiratory functions and rumen contraction rate.

@article{Doherty1988EvaluationOS,
  title={Evaluation of sedative R51703 in cattle: effects on cardiorespiratory functions and rumen contraction rate.},
  author={T. Doherty and A. Valverde and A. Valliant},
  journal={Canadian journal of veterinary research = Revue canadienne de recherche veterinaire},
  year={1988},
  volume={52 4},
  pages={
          481-3
        }
}
R51703, a substance with 5-hydroxytryptamine type 2 receptor antagonist properties, was studied to assess its potential as a sedative in cattle. Six cattle in the study group were given R51703 intramuscularly at a dose rate of 0.15 mg/kg. Sedation became obvious between 10 and 15 minutes postinjection in five of these animals and lasted for approximately 120 minutes. No significant changes (P less than or equal to 0.05) were observed in respiratory rate, arterial blood gas, acid-base values or… Expand
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References

Alleviation of excessive gas accumulation in the ruminant stomach by ritanserin.