Evaluation of resuscitation fluids on endothelial glycocalyx, venular blood flow, and coagulation function after hemorrhagic shock in rats

@article{Torres2013EvaluationOR,
  title={Evaluation of resuscitation fluids on endothelial glycocalyx, venular blood flow, and coagulation function after hemorrhagic shock in rats},
  author={L. Torres and J. Sondeen and L. Ji and M. Dubick and I. T. Filho},
  journal={Journal of Trauma and Acute Care Surgery},
  year={2013},
  volume={75},
  pages={759–766}
}
BACKGROUND Endothelial glycocalyx (EG) plays an essential role in endothelium integrity and may be compromised by hemorrhagic shock. The effects of currently available resuscitation fluids such as Hextend (HEX) or lactated Ringer’s solution (LR) on vascular function and coagulation are not well understood. The aim of the present study was to compare the effects of fresh frozen plasma (FFP) with HEX or LR in their ability to repair EG structure, promote volume expansion, increase blood flow, and… Expand
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