Evaluation of response to treatment using DCE-MRI: the relationship between initial area under the gadolinium curve (IAUGC) and quantitative pharmacokinetic analysis.

@article{WalkerSamuel2006EvaluationOR,
  title={Evaluation of response to treatment using DCE-MRI: the relationship between initial area under the gadolinium curve (IAUGC) and quantitative pharmacokinetic analysis.},
  author={Simon Walker-Samuel and Martin O. Leach and David J. Collins},
  journal={Physics in medicine and biology},
  year={2006},
  volume={51 14},
  pages={3593-602}
}
The initial area under the gadolinium curve (IAUGC) is often used in addition to or as an alternative to parameters derived from pharmacokinetic modelling of T1-weighted dynamic contrast-enhanced (DCE) MRI data in the assessment of response to treatment of cancer. However, the physiological meaning of the IAUGC has not been rigorously defined with respect to model-based parameters. Here, simulations of DCE-MRI data were used to investigate the relationship between IAUGC and the parameters K… CONTINUE READING

From This Paper

Topics from this paper.
49 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

Similar Papers

Loading similar papers…