Evaluation of proteoglycan gene polymorphisms as risk factors in the genetic susceptibility to high myopia.

Abstract

PURPOSE. To investigate the relationship between high myopia and single nucleotide polymorphisms (SNPs) in six proteoglycan genes: aggrecan (ACAN), fibromodulin (FMOD), decorin (DCN), lumican (LUM), keratocan (KERA), and epiphycan (EPYC). These genes were selected for study because they are involved in induced myopia in animals and/or are within the human… (More)
DOI: 10.1167/iovs.11-7639

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