Evaluation of protein expression and DNA methylation profiles detected by pyrosequencing in invasive breast cancer.

@article{Zmetakova2013EvaluationOP,
  title={Evaluation of protein expression and DNA methylation profiles detected by pyrosequencing in invasive breast cancer.},
  author={Iveta Zmetakova and L'udov{\'i}t Danihel and B Smolkova and Michal Mego and Viera Horvathova Kajabova and Tomas Krivulcik and I I Rusnak and Boris R{\'y}chly and Du{\vs}an Dani{\vs} and Vanda Repisk{\'a} and Peter Blasko and Marian Karaba and Juraj Benca and Juraj Pechan and Ivana Fridrichova},
  journal={Neoplasma},
  year={2013},
  volume={60 6},
  pages={635-46}
}
Breast carcinoma is the most common cancer with high mortality caused by metastatic disease. New molecular biomarkers predicting the tumour's metastatic potential would therefore improve metastasis prevention and personalised care. The aim of the study was to investigate the relationship between DNA methylation levels in invasivity and metastasising associated genes with aberrant protein expression and also to evaluate whether a similar DNA methylation level is present in the tumour and… CONTINUE READING

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