Evaluation of potential of Zn-pectinate gel (ZPG) microparticles containing mesalazine for colonic drug delivery

@inproceedings{Kawadkar2010EvaluationOP,
  title={Evaluation of potential of Zn-pectinate gel (ZPG) microparticles containing mesalazine for colonic drug delivery},
  author={Jitendra Kawadkar and K. Chauhan Meenakshi and Alpana Ram},
  booktitle={Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences},
  year={2010}
}
BACKGROUND AND THE PURPOSE OF THE STUDY Pectin derivatives have been utilized for colonic drug delivery (CDD). In this study the effects of different formulation variables upon the characteristics of pectinate microparticles (MPs) prepared by ionotropic gelation technique for colonic delivery of mesalazine was investigated. METHODS In-vitro drug release of MPs was studied using USP XXIV dissolution apparatus type I, in different fluids e.g. simulated gastric fluid (SGF: pH 1.2), simulated… CONTINUE READING

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