Evaluation of polyamidoamine dendrimers as potential carriers for quercetin, a versatile flavonoid.

@article{Madaan2016EvaluationOP,
  title={Evaluation of polyamidoamine dendrimers as potential carriers for quercetin, a versatile flavonoid.},
  author={Kanika Madaan and Viney Lather and Deepti Pandita},
  journal={Drug delivery},
  year={2016},
  volume={23 1},
  pages={254-62}
}
The aim of the present research work was to investigate the potential of polyamidoamine (PAMAM) dendrimers as oral drug delivery carriers for quercetin, a Biopharmaceutical Classification System (BCS) class II molecule. The aqueous solubility of quercetin was investigated in different generations of dendrimers, i.e. G0, G1, G2 and G3, with varying concentrations (0.1, 0.5, 1, 2 and 4 µM). Then, it was successfully incorporated in PAMAM dendrimers and they were characterized for incorporation… CONTINUE READING
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