Evaluation of percutaneous permeation of repellent DEET and sunscreen oxybenzone from emulsion-based formulations in artificial membrane and human skin

  title={Evaluation of percutaneous permeation of repellent DEET and sunscreen oxybenzone from emulsion-based formulations in artificial membrane and human skin},
  author={Tao Wang and Donald Miller and Frank Burczynski and Xiaochen Gu},
  journal={Acta Pharmaceutica Sinica. B},
  pages={43 - 51}
Insect repellent DEET and sunscreen ingredient oxybenzone play an essential role in minimizing vector-borne diseases and skin cancers. The purpose of this study was to investigate the effects of emulsion type, addition of thickening agent and droplet size in three emulsion-based lotions on percutaneous permeation of DEET and oxybenzone using in vitro diffusion experiments, in order to minimize overall systemic permeation of the substances. Formulation C (water-in-oil emulsion) significantly… 
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  • 2002
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    Journal of controlled release : official journal of the Controlled Release Society
  • 2000
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