Evaluation of p53, PCNA, Ki-67, MDM2 and AgNOR in oral peripheral and central giant cell lesions.

@article{Souza2000EvaluationOP,
  title={Evaluation of p53, PCNA, Ki-67, MDM2 and AgNOR in oral peripheral and central giant cell lesions.},
  author={Paulo E.A. Souza and Ricardo Alves Mesquita and Ricardo Santiago Gomez},
  journal={Oral diseases},
  year={2000},
  volume={6 1},
  pages={35-9}
}
OBJECTIVES Peripheral giant cell lesion (PGCL) and central giant cell lesion (CGCL) of the jaws have a distinct clinical behaviour. Whether such biological differences are supported by a distinct pattern of proliferation markers or cell cycle associated proteins expression is not known. Therefore the purpose of the present study was to compare the immunohistochemical expression of p53, MDM2, Ki-67, PCNA and the histochemical expression of argyrophilic nuclear organiser region (AgNOR) on PGCL… CONTINUE READING

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