Evaluation of nonradioactive, colored microspheres for measurement of regional myocardial blood flow in dogs.

  title={Evaluation of nonradioactive, colored microspheres for measurement of regional myocardial blood flow in dogs.},
  author={Sharon L. Hale and Kevin J. Alker and Robert A. Kloner},
  volume={78 2},
Measurement of regional myocardial blood flow (RMBF) is crucial in experimental studies of myocardial ischemia and reperfusion in dogs. The standard measurement technique uses radioactive microspheres; however, not all institutions are able to dispose of radioactive waste and therefore cannot make use of this method. We tested a new, nonradioactive microsphere, labeled with colors instead of nuclides. Simultaneous blood flow measurements with two nuclide-labeled and two colored microspheres… CONTINUE READING
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Publications referenced by this paper.
Showing 1-9 of 9 references

Total and regional myocardial blood flow measurements with 25 , u , 15 , , 9 / l , and filtered 1l 0 , u diameter microspheres and antipyrine in dogs and sheep

J Utley, E Carlson, Hoffman JIE, HM Martinez, GD Buckburg
Circ Res • 1974

The course of the blood through the heart of the fetal mammal , with a note on the reptilian and amphibian circulations

AG Pohlman
Anat Rec • 1909