Evaluation of nonradioactive, colored microspheres for measurement of regional myocardial blood flow in dogs.

@article{Hale1988EvaluationON,
  title={Evaluation of nonradioactive, colored microspheres for measurement of regional myocardial blood flow in dogs.},
  author={Sharon L. Hale and Kevin J. Alker and Robert A. Kloner},
  journal={Circulation},
  year={1988},
  volume={78 2},
  pages={
          428-34
        }
}
Measurement of regional myocardial blood flow (RMBF) is crucial in experimental studies of myocardial ischemia and reperfusion in dogs. The standard measurement technique uses radioactive microspheres; however, not all institutions are able to dispose of radioactive waste and therefore cannot make use of this method. We tested a new, nonradioactive microsphere, labeled with colors instead of nuclides. Simultaneous blood flow measurements with two nuclide-labeled and two colored microspheres… CONTINUE READING
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