Evaluation of nitroreductase and acetyltransferase participation in N-nitrosodiethylamine genotoxicity.

@article{Aiub2006EvaluationON,
  title={Evaluation of nitroreductase and acetyltransferase participation in N-nitrosodiethylamine genotoxicity.},
  author={Claudia A F Aiub and Jos{\'e} Luiz Mazzei and Lu{\'i}s Felipe Ribeiro Pinto and Israel Felzenszwalb},
  journal={Chemico-biological interactions},
  year={2006},
  volume={161 2},
  pages={146-54}
}
N-Nitroso compounds, such as N-nitrosodiethylamine (NDEA), are a versatile group of chemical carcinogens, being suspected to be involved in gastrointestinal tumors in humans. The intestinal microflora can modify a wide range of environmental chemicals either directly or in the course of enterohepatic circulation. Nitroreductases from bacteria seem to have a… CONTINUE READING