Evaluation of nicked human chorionic gonadotropin content in clinical specimens by a specific immunometric assay.

@article{Kovalevskaya1999EvaluationON,
  title={Evaluation of nicked human chorionic gonadotropin content in clinical specimens by a specific immunometric assay.},
  author={Galina Kovalevskaya and Steven Birken and Tetsuya Kakuma and John P Schlatterer and John F O'Connor},
  journal={Clinical chemistry},
  year={1999},
  volume={45 1},
  pages={68-77}
}
We report the development and characterization of an IRMA for the direct measurement of nicked human chorionic gonadotropin (hCGn) in blood and urine. hCGn derived from a reference preparation of hCG used as an immunogen elicits monoclonal antibodies (mAbs) with enhanced recognition of human luteinizing hormone epitopes. The most specific assay for pregnancy hCGn is an IRMA composed of one mAb to choriocarcinoma-derived hCGn (C5) and a second mAb developed from immunization with normal… CONTINUE READING

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A microcolorimetric determination of creatine in urine by the Jaffe reaction.

The Journal of biological chemistry • 1954
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