Evaluation of next-generation sequencing software in mapping and assembly

  title={Evaluation of next-generation sequencing software in mapping and assembly},
  author={Suying Bao and Rui Jiang and WingKeung Kwan and Binbin Wang and Xu Ma and You-Qiang Song},
  journal={Journal of Human Genetics},
Next-generation high-throughput DNA sequencing technologies have advanced progressively in sequence-based genomic research and novel biological applications with the promise of sequencing DNA at unprecedented speed. These new non-Sanger-based technologies feature several advantages when compared with traditional sequencing methods in terms of higher sequencing speed, lower per run cost and higher accuracy. However, reads from next-generation sequencing (NGS) platforms, such as 454/Roche, ABI… CONTINUE READING