Evaluation of new occult blood tests for detection of colorectal neoplasia.

  title={Evaluation of new occult blood tests for detection of colorectal neoplasia.},
  author={D James B St John and Graeme P. Young and M A Alexeyeff and Maureen Deacon and A. M. Cuthbertson and Finlay A. Macrae and Joanna Penfold},
  volume={104 6},
BACKGROUND Hemoccult II, the guaiac-based fecal occult blood test used in most colorectal cancer screening programs, has an unsatisfactory sensitivity for asymptomatic colorectal neoplasms. We evaluated the relative performance of four fecal occult blood tests, directed against various components of the hemoglobin molecule. METHODS All tests, Hemoccult II, HemoccultSENSA (a more sensitive guaiac test), HemeSelect (an immunochemical test specific for human hemoglobin), and HemoQuant (the heme… CONTINUE READING

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