Evaluation of new anti-infective drugs for surgical prophylaxis. Infectious Diseases Society of America and the Food and Drug Administration.

@article{Gorbach1992EvaluationON,
  title={Evaluation of new anti-infective drugs for surgical prophylaxis. Infectious Diseases Society of America and the Food and Drug Administration.},
  author={Sherwood L. Gorbach and Robert E. Condon and John E. Conte and Allen B. Kaiser and William J. Ledger and Ronald Lee Nichols},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={1992},
  volume={15 Suppl 1},
  pages={
          S313-38
        }
}
It has been established by substantial research that antimicrobial prophylaxis for various surgical procedures can reduce the risk of postoperative morbidity and mortality. When the incidence of infectious complications is high, the reduction with prophylaxis is most dramatic. However, even for many "clean" procedures (vascular procedures, total joint replacement), the small reduction in potentially calamitous complications justifies the use of prophylaxis. Many issues of detail remain… CONTINUE READING

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Clinical practice guidelines for antimicrobial prophylaxis in surgery.

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