Evaluation of napsin A, cytokeratin 5/6, p63, and thyroid transcription factor 1 in adenocarcinoma versus squamous cell carcinoma of the lung.

@article{Whithaus2012EvaluationON,
  title={Evaluation of napsin A, cytokeratin 5/6, p63, and thyroid transcription factor 1 in adenocarcinoma versus squamous cell carcinoma of the lung.},
  author={Kenneth Whithaus and Junya Fukuoka and Thomas J. Prihoda and Jaishree Jagirdar},
  journal={Archives of pathology & laboratory medicine},
  year={2012},
  volume={136 2},
  pages={155-62}
}
CONTEXT The distinction of lung adenocarcinoma from other types of primary lung malignancies is important clinically. Accurate morphologic classification is often hindered because 70% of lung cancers are diagnosed on limited fine-needle aspiration or transbronchial biopsy specimens. Although thyroid transcription factor 1 (TTF-1) has historically been the most specific marker for lung adenocarcinoma, a relatively new marker, napsin A, has recently been shown to be more sensitive and specific… CONTINUE READING
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