Evaluation of multiplex assay platforms for detection of influenza hemagglutinin subtype specific antibody responses.

@article{Li2017EvaluationOM,
  title={Evaluation of multiplex assay platforms for detection of influenza hemagglutinin subtype specific antibody responses.},
  author={Zhu-Nan Li and Kimberly M Weber and Rebecca A Limmer and Bobbi Jo Horne and James V. Stevens and Joy Wu Schwerzmann and Jens Wrammert and Megan McCausland and Andrew J Phipps and Kathy Hancock and Daniel B. Jernigan and Min Z. Levine and Jacqueline M. Katz and Joseph D. Miller},
  journal={Journal of virological methods},
  year={2017},
  volume={243},
  pages={61-67}
}
Influenza hemagglutination inhibition (HI) and virus microneutralization assays (MN) are widely used for seroprevalence studies. However, these assays have limited field portability and are difficult to fully automate for high throughput laboratory testing. To address these issues, three multiplex influenza subtype-specific antibody detection assays were developed using recombinant hemagglutinin antigens in combination with Chembio, Luminex®, and ForteBio® platforms. Assay sensitivity… CONTINUE READING