Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies.

@article{Allenspach2010EvaluationOM,
  title={Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies.},
  author={K Allenspach and Arthur K House and Kina Smith and Fergus McNeill and Anke Hendricks and Jocelyn G. Elson-Riggins and Anna M Riddle and J{\"o}rg Manfred Steiner and Dirk Werling and Oliver A. Garden and Brian Catchpole and Jan S Suchodolski},
  journal={Veterinary microbiology},
  year={2010},
  volume={146 3-4},
  pages={326-35}
}
The pathogenesis of chronic enteropathies in dogs likely involves an interaction between the intestinal immune system and luminal intestinal bacteria. German shepherd dogs (GSD) are particularly predisposed to chronic enteropathies. The present study sought to evaluate expression patterns of certain pattern recognition receptors of the innate immunity (Toll-like receptors, TLR), clinical disease activity and histopathological severity in GSD with chronic enteropathies. Mucosal biopsies were… CONTINUE READING