Evaluation of mineralized collagen and alpha-tricalcium phosphate as scaffolds for tissue engineering of bone using human mesenchymal stem cells.

@article{Niemeyer2004EvaluationOM,
  title={Evaluation of mineralized collagen and alpha-tricalcium phosphate as scaffolds for tissue engineering of bone using human mesenchymal stem cells.},
  author={Philipp Niemeyer and Ulf Krause and Joerg Fellenberg and Philip Kasten and Anja Seckinger and Anthony D. Ho and Hans-Georg Simank},
  journal={Cells, tissues, organs},
  year={2004},
  volume={177 2},
  pages={68-78}
}
Owing to their plasticity and high proliferation capacity in vitro, mesenchymal stem cells (MSC) isolated from human bone marrow are promising candidates for use in tissue engineering approaches for the repair or replacement of mesenchymal tissues such as bone, cartilage or tendon. In keeping with the tissue engineering concept, these cells are cultivated on three-dimensional (3D) scaffolds to replace 3D tissue defects. Among the scaffolds tested for tissue engineering of bone, those containing… CONTINUE READING