Evaluation of microsatellite analysis in urine sediment for diagnosis of bladder cancer.

@article{Schneider2000EvaluationOM,
  title={Evaluation of microsatellite analysis in urine sediment for diagnosis of bladder cancer.},
  author={Aurelia Schneider and S Borgnat and Hai-li Lang and O R{\'e}gine and V{\'e}ronique Lindner and Moustapha Kassem and Christian Saussine and P. Oudet and Didier Jacqmin and Marie Pierre Gaub},
  journal={Cancer research},
  year={2000},
  volume={60 16},
  pages={4617-22}
}
Alterations at microsatellite DNA markers in cells exfoliated in urine have been correlated to the presence of bladder cancer. To check the feasibility of such noninvasive analysis to routinely diagnose bladder cancers, we have developed a highly sensitive method using fluorescent PCR to search for DNA microsatellite alterations in urine sediment compared with a blood paired sample. One hundred eighty-three patients were included in our study. This population comprised 103 bladder cancers (64… CONTINUE READING
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