Evaluation of micronucleus induction in lymphocytes of patients following boron-neutron-capture-therapy: a comparison with thyroid cancer patients treated with radioiodine.

@article{Kinashi2007EvaluationOM,
  title={Evaluation of micronucleus induction in lymphocytes of patients following boron-neutron-capture-therapy: a comparison with thyroid cancer patients treated with radioiodine.},
  author={Yuko Kinashi and Yoshinori Sakurai and Shinichiro Masunaga and Minoru Suzuki and Kenji Nagata and Koji Ono},
  journal={Journal of radiation research},
  year={2007},
  volume={48 3},
  pages={197-204}
}
This study evaluated micronuclei induction in peripheral T-lymphocytes after BNCT (boron neutron capture therapy) irradiation of 15 brain tumor and 20 head-and-neck cancer patients. In all of these patients, the micronucleus frequency increased after BNCT; the number of micronuclei per 1000 binucleated T-lymphocytes after BNCT increased by 33.0 +/- 12.2 for brain tumor patients and 22.8 +/- 10.3 for head-and-neck cancer patients. In 14 thyroid cancer patients who were administered radioiodine… CONTINUE READING