Evaluation of metallic and polymeric biomaterial surface energy and surface roughness characteristics for directed cell adhesion.

  title={Evaluation of metallic and polymeric biomaterial surface energy and surface roughness characteristics for directed cell adhesion.},
  author={Nadim James Hallab and Kirk J. Bundy and K. O'Connor and Rachael L Moses and Joshua J. Jacobs},
  journal={Tissue engineering},
  volume={7 1},
Directed cell adhesion remains an important goal of implant and tissue engineering technology. In this study, surface energy and surface roughness were investigated to ascertain which of these properties show more overall influence on biomaterial-cell adhesion and colonization. Jet impingement was used to quantify cellular adhesion strength. Cellular proliferation and extracellular matrix secretion were used to characterize colonization of 3T3MC fibroblasts on: HS25 (a cobalt based implant… 

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