Evaluation of melatonin treatment in primary culture of canine mammary tumors.

@article{Lopes2015EvaluationOM,
  title={Evaluation of melatonin treatment in primary culture of canine mammary tumors.},
  author={Juliana Ramos Lopes and Larissa Bazela Maschio and Bruna Victorasso Jardim-Perassi and Marina Gobbe Moschetta and L{\'i}via de Carvalho Ferreira and Gustavo Rodrigues Martins and Gabriela Bottaro Gelaleti and Debora A P C Zuccari},
  journal={Oncology reports},
  year={2015},
  volume={33 1},
  pages={311-9}
}
Mammary neoplasias are the most common tumors observed in female dogs. Identification of these tumors is valuable in order to identify beneficial therapeutic agents as alternative treatments for this tumor type. Oral administration of melatonin appears to exert an oncostatic effect on mammary neoplasia and may have a possible mechanism of action through its interaction with estrogen receptors on epithelial cells. Hence, we analyzed the potential therapeutic value of melatonin in tumors that are… CONTINUE READING