Evaluation of low dose prostaglandin E1 treatment for ductus dependent congenital heart disease

@article{Kramer1995EvaluationOL,
  title={Evaluation of low dose prostaglandin E1 treatment for ductus dependent congenital heart disease},
  author={H. Kramer and Michael Bech Sommer and Spyros Rammos and Otto Nils Krogmann},
  journal={European Journal of Pediatrics},
  year={1995},
  volume={154},
  pages={700-707}
}
This study reports our experience with low-dose prostaglandin E1 (PGE1) treatment of 91 newborns with ductus dependent congenital heart disease (CHD). PGE1 efficacy, side-effects as well as the cardiovascular and respiratory profile of the patients were analysed. PGE1 doses > 0.02 μg/kg per minute were used for only 5.3% of the total 23 656 h of treatment. The mean systolic blood pressures did not differ from the normal mean for patients with cyanotic CHD, while the diastolic values were… CONTINUE READING
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