Evaluation of long-term potentiation of small compound and unitary EPSPs at the hippocampal CA3-CA1 synapse.

@article{Friedlander1990EvaluationOL,
  title={Evaluation of long-term potentiation of small compound and unitary EPSPs at the hippocampal CA3-CA1 synapse.},
  author={Michael J. Friedlander and Robert J. Sayer and Stephen J. Redman},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1990},
  volume={10 3},
  pages={814-25}
}
Long-term potentiation (LTP) was evaluated for small monosynaptic CA3-mediated EPSPs in CA1 neurons in the guinea pig hippocampal slice. Small EPSPs included those elicited by stimulation of Schaffer axon collaterals of several CA3 neurons (160-480 microV amplitude, n = 40 EPSPs in 40 neurons) and those elicited by stimulation of an individual CA3 neuron (89-563 microV amplitude, n = 14 EPSPs in 11 neurons). Various protocols were employed to induce LTP and were deemed successful as evaluated… CONTINUE READING